Low molecular weight phosphotyrosine protein phosphatases as emerging targets for the design of novel therapeutic agents

J Med Chem. 2012 Jan 12;55(1):2-22. doi: 10.1021/jm200607g. Epub 2011 Oct 26.
No abstract available

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use
  • Antitubercular Agents / chemistry
  • Antitubercular Agents / pharmacology
  • Diabetes Mellitus / drug therapy
  • Diabetes Mellitus / enzymology
  • Humans
  • Hypoglycemic Agents / pharmacology
  • Insulin Resistance
  • Isoenzymes / antagonists & inhibitors
  • Isoenzymes / chemistry
  • Isoenzymes / physiology
  • Models, Molecular
  • Molecular Targeted Therapy
  • Mycobacterium tuberculosis / enzymology
  • Neoplasms / drug therapy
  • Neoplasms / enzymology
  • Protein Conformation
  • Protein Tyrosine Phosphatases / antagonists & inhibitors*
  • Protein Tyrosine Phosphatases / chemistry
  • Protein Tyrosine Phosphatases / physiology*
  • Proto-Oncogene Proteins / antagonists & inhibitors*
  • Proto-Oncogene Proteins / chemistry
  • Proto-Oncogene Proteins / physiology*

Substances

  • Antineoplastic Agents
  • Antitubercular Agents
  • Hypoglycemic Agents
  • Isoenzymes
  • Proto-Oncogene Proteins
  • ACP1 protein, human
  • Protein Tyrosine Phosphatases